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MELTING 5.0.3

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MELTING Description

MELTING - Compute the enthalpy and the entropy of the helix coil transition for a nucleic acid duplex.

Compute the enthalpy and the entropy of the helix coil transition for a nucleic acid duplex.

MELTING is an open source application that was designed in order to provide you with a simple means of computing, for a nucleic acid duplex, the enthalpy and the entropy of the helix coil transition and afterwards the melting temperature.

Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed.

The set of thermodynamic parameters can be easely changed, for instance following an experimental breakthrough.

MELTING 4 is written in ISO C and MELTING 5 in Java.

MELTING 5.0.3 is licensed as Freeware for the Windows operating system / platform. MELTING is provided as a free download for all software users (Freeware).

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MELTING Download Notice
MELTING is periodically updated by FileCluster but you may encounter situations when the software informations are slightly out-of-date, the producers of MELTING can modify the product without notifying us. MELTING 5.0.3 is currently the last updated version of the software. All rights for MELTING are belong to the developer, Nicolas Le Novère and Marine Dumousseau.

Any form of support or software problems regarding MELTING will be addressd to its developers. Please be aware that we do NOT provide MELTING cracks, serial numbers, registration codes or any forms of pirated software downloads.
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